Retrograde and oscillatory shear increase across the menopause transition
نویسندگان
چکیده
منابع مشابه
α-adrenergic vasoconstriction contributes to the age-related increase in conduit artery retrograde and oscillatory shear.
Aging is associated with increased retrograde and oscillatory shear in peripheral conduit arteries of humans. Although the mechanisms responsible for these age-related changes are not completely understood, augmented downstream α-adrenergic tone likely plays a significant role in this phenomenon. Therefore, in protocol 1, brachial artery diameter and blood velocity were measured via Doppler ult...
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Vascular aging, featuring endothelial dysfunction and large artery stiffening, is a major risk factor for developing cardiovascular disease (CVD). In women, vascular aging appears to be accelerated during the menopause transition, particularly around the late perimenopausal period, presumably related to declines in ovarian function and estrogen levels. The mechanisms underlying endothelial dysf...
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BACKGROUND Acute doses of elevated retrograde shear rate (SR) appear to be detrimental to endothelial function in resting humans. However, retrograde shear increases during moderate intensity exercise which also enhances post-exercise endothelial function. Since SR patterns differ with the modality of exercise, it is important to determine if augmented retrograde SR during exercise influences p...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2019
ISSN: 2051-817X
DOI: 10.14814/phy2.13965